China Anti-Hair Loss 99% Pure Minoxidil Setipiprant CB-03-01 Ru58841 Powder CAS 38304-91-5

Anti-Hair Loss 99% pure Minoxidil Setipiprant CB-03-01 RU58841 powder CAS 38304-91-5

Physical Characters and specifications

Product nameMinoxidil CAS No.38304-91-5Molecular FormulaC9H15N5OMolecular weight209.25EINECS NO.253-874-2Grade StandardMedicine GradeCOAPlease contact with Senwayer freely

ItemSpecifications AppearanceWhite or almost white crystalline powder.Purity99%minMelting point272-274ºCBoiling point348.61ºCDensity1.1651Refractive index1.7610Flash point166.5±28.7ºCAcidity coefficient (pKa)4.61(at 25ºC)SolubilitySlightly soluble in water, soluble in methanol and in propylene glycol.Storage condition-20ºCShelf life3 years

Product Introduction

Minoxidil was the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss). Before that, minoxidil had been used as vasodilator drug prescribed as oral tablet to treat high blood pressure, with side effects that included hair growth and reversal of male baldness.Since the 1990s, numerous generic forms of minoxidil have become available to treat hair loss while the oral form is still used to treat high blood pressure.

Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. It is available over the counter for treatment of androgenic alopecia, among other baldness treatments, but measurable changes disappear within months after discontinuation of treatment. Its effectiveness has largely been demonstrated in younger men (18 to 41 years of age), the younger the better.

Minoxidil is a potassium channel agonist. It contains the chemical structure of nitric oxide), a blood vessel dilator, and may be a nitric oxide agonist. This appears to explain its vasodilatory effects, but may also be linked to minoxidil's ability to stimulate hair growth and treat hair loss. Since minoxidil is a nitric oxide-related compound, it was suspected to act via activation of guanylate cyclase, an enzyme involved in vasodilation.

Function Minoxidil
1. Minoxidil powder needs to be applied once or twice daily for hair to be maintained.
2. For maximum effect, the solution should be in contact with the scalp for hours before being washed out. It does not seem capable of reducing DHT or the enzyme responsible for its accumulation around the hair follicle, 5-aliha reductase, which are the main causes of male pattern baldness in genetically susceptible individuals. Therefore, when treatment is stopped, the DHT already accumlated around the follicle has its expected effect, and the follicle usually shrinks again and eventually dies.
3.Minoxidil powder can promote hair regrowth,slow or stop hair loss and treat high blood pressure.

RU58841
RU58841 is the drug for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of RU58841have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery.

Setipiprant
Setipiprant is the drug for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of Setipiprant have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery.