China Chemical 540737-29-9 Tofacitinib Citrate

Beijing Mesochem Technology Co., Ltd is located in national economic and technological development of Yizhuang, which is a gathering place of world's top 500 enterprises. Devoting to pDrilling Tools harmaceutical chemicals, find chemicals, and fundamental chemical material, Mesochem owns independent right of import and export.based on abundant resources from Beijing various colleges and universities, Mesochem focused on incessant innovation along with research and development of new products.
CertificateofAnalysis
Product Name: Tofacitinib Citrate
CASNo.:540737-29-9
BatchNo.HF161021Quantity3.66kgsMfg. DateOct.21, 2016PackageAs requiredCompressor Rep. DateOct. 23, 2016Exp. DateOct. 20, 2018ItemsStandardsResultsAppearanceWhite or off-white solid powderWhite solid powderIdentificationBy IRCompliesBy HPLCCompliesSolubilitySlightly soluble in water, very slightly soluble in methanol, hardly insoluble in ethanol, acetone and acetonitrileCompliesSpecific Rotation+9.0°~ +13.0°(0.6g/100ml in DMSO)+10.0°Loss on Drying≤0.50%0.25%HeavyMetal≤10ppmCompliesResidue on Ignition≤0.20%0.10%Electrical Control System Enantiomer(SS) ≤0.1%NDCitrate36.2% ~ 40.0% (on dried basis)38.3%Residual SolventsPetroleum ether: ≤3000ppmNDEthanol: ≤5000ppmNDEthyl ether: ≤5000ppmNDAcetone: Other Instruments & Meters ≤5000ppmNDn-Butyl alcohol: ≤5000ppmNDDichloromethane: ≤600ppmNDRelatedSubstances(RS+SR): ≤0.10%NDAny single impurity: ≤0.10%0.05%Total Impurities: ≤0.30%0.07%Assay
(HPLC basis on drying)99.0%~101.0%99.85%Reference StandardIn-house StandardConclusionThe productcompliedtoIn-housestandard.StoragePreserve in tight,light-resistant containers in a cool place