China Levamisole HCl CAS16595-80-5

Levamisole Hydrochloride is the hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunomodulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis.

Levamisole Hydrochloride (Levamisole HCL), is an anthelmintic (anti-worm) agent commonly used in large livestock such as cattle, pigs and sheep. In 1971 it was found to have immunostimulatory properties and investigation into its use in humans began to expand. Currently, Levamisole HCL is used in humans for diseases related to imbalances in the regulation of immune responses or deficiencies of the immune system, including autoimmune diseases, chronic and recurrent diseases, chronic infections and cancer. It has beneficial effects on host defense mechanisms and restores depressed immune responses in animals and humans. Another interesting use of levamisole in humans is as a treatment for common warts ().

News of its anthelmintic efficacy and immune system benefits has been known among aquatic hobbyists for years. The problem however, is that there is not much in the way of definitive information on its use and application in the hobby. Anecdotal accounts of how it has worked for those 'outside the box' aquarists who first braved its use with fish, and accounts of personal experience with Levamisole in individual aquariums are helpful, but the 'your mileage may vary' factor is immense. Word about its usefulness in treating internal parasites in the ornamental fish trade has spread, but information regarding its use is limited and sometimes conflicting. From the information I have found thus far, Levamisole HCL is safe to use in aquaria and effective against many internal parasites, especially nematodes, when used in appropriate dosages. It does not harm the bio-filter, plants, invertebrates or uninfected fish. As an added benefit, it boosts the immune competence of fish, humans, large animals, birds and some reptiles.