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Min. Order / Reference FOB Price | |
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1 kg | US $1.00/ kg |
Local Area: | Zhuzhou, Hunan, China |
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R&D Capacity: | OEM, ODM, Other |
Payment Terms: | T/T, WesternUnion |
CAS No.: | 145-13-1 |
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Formula: | C21h32o2 |
EINECS: | / |
Product name
Pregnenolone
CAS Instrument Box register number
145-13-1
Molecular formula
C21H32O2
Molecular weight
316.48
Appearance
White or almost white crystalline powder
Assay
99%
Usage
Use for biochemical studies. Progesterone hormone class medicine intermediate
Standard
USP/BP
Price
Negotiated
Minimum order quantity
Negotiated
Package
Exquisite and can according to customers' requirement
Shipping leading time
Within 8hours after receiving the payment
Payment options
Western Union, MoneyGram, bank transfer (TT), Bitcoin
Shipping
Express delivery with DHL, EMS, Fedex, HKEMS, TNT, UPS (within 5-7days after payment)
CAS:145-13-1
MF:C21H32O2
MW:316.48
EINECS:205-647-4
Melting point:188-190 °C
alpha 28.5 º(c=1, EtOH)
Boiling point:395.89°C (rough estimate)
Density 1.0382 (rough estimate)
refractive index 1.5344 (estimate)
Flash point:9ºC
storage temp. Refrigerator
solubility ethanol: soluble10mg/mL, clear, colorless to faintly yellow
form Powder
color White to off-white
Description:
Pregnenolone can be converted to progesterone. With 3-hydroxysteroid dehydrogenase and 4-5 isomerase, the key enzyme steps are twofold. The latter transfers tDrilling Rig he double bond on the Aring from C5 to C4. Progesterone is asubstance that enters the delta-4 pathway and produces 17-hydroxyprogesterone and androstenedione, which are precursors for testing estrone and estrone. Aldosterone and corticosteroids are also derived from progesterone or its derivatives.
Pregnenolone can be converted to 17-hydroxy-pregnenolone 17α-hydroxylase (CYP17A1) by enzyme. Using this route called delta-5, the next step is to convert to dehydroepiandros terone (DH EA) using ade-saccharification enzyme. DH EA is the precursor of andros tenedione.
Pregnenolone can be converted to androgen-5,16-dien-3-ol by 16-ene synthase.
Pregnenolone is anatural hormone that cannot be patented. As early as the 1940s, when researchers began experimenting with it, they realized that it might help people with stress, and it might increase the energy of those who are tired. However, at about the same time, another closely related hormone cortisol was found. Cortisol stole the spotlight. When cortisol is administered to patients with rheumatoid arthritis, the short-term effect is significaIndustrial D Printer ntly improved. These eye-catching photos of rehabilitation have been circulated, and the medical community is very impressed. Scientists basically put pregnenolone aside and focus on cortisol. The structure of cortisol has changed, producing similar molecules such as dexamethasone and prednisone, astronger steroid hormone. Dexamethasone and other similar glucocorticoids can be patented, so pharmaceutical companies can make alot of money. Pregnenolone has been in arelatively unknown state since the 1940s and is rarely mentioned in the medical literature. In recent years, studies on pregnenolone have rarely been published, and only afew have been studied in human subjects.