China Supply High Purity Ademetionine 1 4-Butanedisulfonate Power for Liver Cirrhosis with Best Price CAS No.: 101020-79-5

Identification

NameAdemetionine 1,4-ButanedisulfonateAbbreviationSAM-BStructure


Other name1,4-butanedisulfonate (salt);
1,4-butanedisulfonate (salt) (2:1:2);
S-Adenosylmethione-1,4-butanedisulfonate;
S-Adenosyl-L-methionine 1,4-butanedisulfonate sodium saltUsesUsed in the therapy of depression, arthritis, chronic hepatitis and cholestasia;Moreover, it can be used in the preventation of liver cancer, or relieve the poisoning of chemicals, alcohol and cancer to liver, improve the curing of wound and growth of cartilage tissue;It also can adjust the function of nerve centre system.AppearanceWhite or off-white powderContent≥98%ClarityClarifyRelated substances≤ 2%CAS NO.101020-79-5Molecular FormulaC15H23N6O5S+·C4H9O6S2-·0.65C4H10O6S2Molecular Weight758.55 g/molPacking specification20kg/barrelWater≤0.2%Residue on ignition≤0.1%Heavy metals≤ 0.002%Refractive index≤ 1000 cfu/gSolubilityH2O:Soluble

Ademetionine 1,4-Butanedisulfonate(SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

It is made of APT and Met, is one kind of biological active molecule, It can be used in the therapy of depression, arthritis, chronic hepatitis and cholestasia; moreover, it can be used in the preventation of liver cancer, or relieve the poisoning of chemicals, alcohol and cancer to liver, improve the curing of wound and growth of cartilage tissue; it also can adjust the function of nerve centre system.

1.Ademetionine 1,4-Butanedisulfonate(SAMe) is a coenzyme involved in methyl group transfers. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase (EC 2.5.1.6). Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAMe. Although these anabolic reactions occur throughout the body, most SAMe is produced and consumed in the liver.
2.Ademetionine 1,4-Butanedisulfonate attached to the methionine sulfur atom in SAMe is chemically reactive. This allows donation of this group to an acceptor substrate in transmethylation reactions. More than 40 metabolic reactions involve the transfer of a methyl group from SAMe to various substrates such as nucleic acids, proteins, and lipids.
3.In bacteria, SAMe is bound by the SAMe riboswitch, which regulates genes involved in methionine or cysteine biosynthesis.

Packing & Shipment

Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards.
5) Warehousing and storage:Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.
Certification

Q1:Which kind of payment terms do you accept?
For small order,you can pay by T/T or Western Union ,nomal order by T/T to our company account.
Q2:Can you give me a discount price?
Surely,It depend on your quantity.
Q3:How can I get a sample?
Free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q4:How to confirm the Product Quality before placing orders?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q5:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero.If there is a real quality problem caused by us, we will send you free goods for replacement or refund yo