Pain Killer Powder Levobupivacaine Hydrochloride CAS 27262-48-2

Quick Details ofLevobupivacaine hydrochloride
Product Name: Levobupivacaine hydrochloride
Synonyms: TIMTEC-BB SBB001337
CAS: 27262-48-2
MF: C18H29ClN2O
MW: 324.89
mp: 254 °C (dec.)(lit.)
alpha: -12.5°(c=2, water)
Appearance : white crystalline powder
Application: levobupivacaine is amide local anesthetics
Description ofLevobupivacaine hydrochlorideLevobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.
The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of actioCOA ofLevobupivacaine hydrochloride
Test ItemsSpecificationTest ResultsDescriptionWhite or almost white crystalline powderWhite crystalline powderMelting Point191.0~193.0ºC192ºCLoss of drying≤1.0%0.5%Heavy metal≤20ppm15ppmTLConly one spotonly one spotAssay≥99.5%99.91%ConclusionIt complies with the USP 32.
Levobupivacaine is alocal anesthetic that belongs to the amino amide group. It is the S-enantiomer of bupivacaine. Salbutamol hydrochloride is usually marketed by Abbott under the trade name Chirocaine. Bupivacaine is an amide type local anesthetic. Although it blocks nerve conduction, its membrane stabilization also affects the myocardium. This can lead to fatal cardiotoxicity. Because bupivacaine is widely used in surgery and obstetrics, try to develop safer long-acting local anesthetics.Bupivacaine molecules are racemic compounds. Zambucaine is the S-enantiomer of bupivacaine and is thought to have alower cardiac toxicity potential than the R-enantiomer. The pharmacokinetic parameters of bupivacaine are similar to bupivacaine.Left bupivacaine has been studied in surgical anesthesia and pain management. Can be used for local infiltration, epidural, intrathecal and peripheral nerve block. For epidural analgesia, can be given clonidine. The double-blind comparison of bupivacaine and bupivacaine showed similar anesthetic effects.why choose our company
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