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Supplier Homepage Chemicals Pharmaceutical Intermediate Peptide Mt-2 Hormones Melanotan II Skin Tanning & Shape Slimming

Peptide Mt-2 Hormones Melanotan II Skin Tanning & Shape Slimming

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10 vials US $7.00/ vials
Local Area: Zhuzhou, Hunan, China
R&D Capacity: OEM, ODM, Other
Payment Terms: LC, T/T, PayPal
Type: Pharmaceutical Intermediates
Appearance: Powder
Quality: USP
MT-2
Cas No.: 121062-08-6
Molecular Formula: C50H69N15O9
M.S.:
Molecular Weight: 1024.18
Purity (HPLC): 98.0%
Appearance: White powder
Single Impurity (HPLC): 0.5%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): >80.0%
Water Content(Karl Fischer): <8.0%
Acetate Content(HPIC): <10.0%
Specific Rotation (20/D): -55.0~-65.0°(c=1 1%HAc)
MS(ESI): Consistent
Mass Balance: 95.0~105.0%
package: (10mg/vial,10vial/kit)
Description:
Melanotan II also known as PT-141 was developed by researchers at the University of Arizona College of Medicine. Melanotan II is an analog of the peptide hormone alpha-melanocyte stimulating hormone (?-MSH), this hormone provides atherapeutic tan with the ability to lower the risk of skin cancer, (MSH) also plays an important role in regulating sexual arousal in men and women. Melanotan II has the additional effect of decreasing body fat mass. Melanotan II It is acyclic lactyam analog of alpha-MSH with the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2.
Melanotan II is in aclass of peptide hormone known as Melanocortins (MCs). Melanocortins (MCs) are multifunctional peptide hormones that regulate adiversity of physiological functions. MCs have been implicated in sexual function in animals.
A MC analog, Melanotan II (MTII), can enhance sexual function in human males (erectile activity) and females (increased levels of sexual desire and genital arousal). Unlike other sexual-enhancement drugs, MTII works at the level of the brain, thus eliciting arather natural sexual response with minimal or no undesirable side effects. The actions of the peptide were discovered accidentally while studying the effects of the peptide and related analogs on human skin pigmentation (tanning). Hadley ME (2005).
When to use Melanotan II
Melanotan II requires cumulative dosing to be effective. Depending on the individual, needed cumulative dose will typically be from 10 to 40 mg, with fairer individuals usually requiring amounts at the higher end of the range. Depending on the total amount needed and the daily dosing suitable for the individual, MT-II injections will need to begin at least aweek prior to aneed for improved tanning. More typically, MT-II use should begin at least amonth prior to such need.Melanotan II can also be used on acycled basis to maintain improved ability to tan.Further, Melanotan II can be used on occasion for prosexual effect.How to use Melanotan II for tanning
Melanotan II is typically provided in vials containing 10 mg of lyophilized (freeze-dried) powder. The vials are reconstituted with aconvenient amount of bacteriostatic or sterile water, added to the vial by syringe. An example convenient amount of water is 2.5 mL. When this amount of water is used, the resulting solution contains 4mg of MT-II per mL. If for example wishing to take adose of 1mg, avolume of 0.25 mL, or "25 IU" as marked on an insulin syringe, would be taken by injection. Injection may be subcutaneous, intramuscular, or intravenous, according to personal preference.How to use Melanotan II for prosexual effect
Where there is no physical erectile dysfunction and where at least some degree of psychological libido exists, Melanotan II can greatly increase the tendency to penile erection. The situation can even become like the years of puberty, where scarcely even the beginning of asexual thought or even nothing at all (perhaps an unconscious thought however) produces an erection. General physical fatigue can become irrelevant. These effects will not occur for all individuals, but do occur for many.Prosexual usage requires injection at least about 4-6 hours prior to desired effect. Duration of action can be about 6-12 hours after onset of effect.
Needed dosage is typically about 1mg, but for some even 0.5 mg can be effective. As aguide, dosage should not exceed 2mg.
Because of the associated effect in increasing tendency to tan, frequency of MT-II use for this purpose is generally limited. If wishing this effect frequently, abetter choice is to use PT-141 (bremelanotide,) an MT-II derivative.Pharmacological class of Melanotan II:
Melanotan II is in the class of alphamelanocyte-stimulating hormone (alpha-MSH) mimetics. Alpha-MSH is produced in the pituitary, and activates alpha-melanocyte receptors. MT-II works in the same way.
There are anumber of subtypes of alpha-melanocyte receptors (MC1-5.) Melanotan II is generally non-selective and activates multiple types. Activation of the MC1 receptor promotes skin pigmentation, while activation of the MC4 receptor can enhance tendency to penile erection.
For comparison, PT-141 is selective for the MC4 receptor and therefore promotes penile erection while having little or no effect on skin pigmentation.Potential side effects of Melanotan II:
Melanotan II can have appetite suppressive effects, but rarely to adegree providing either aproblem for bulking or much of an aid for dieting. Where hair is light colored MT-II use can darken it, though the effect on hair is much less than on the skin and generally is unnoticed. It's also possible for feelings of nausea, light-headedness, or tiredness to occur. Any of these undesired effects, if occurring, will clear quickly. Increased growth, increased number, or hyperpigmentation of moles may occur. These side effects, if they occur, may last for asubstantial period of time or even be permanent. Accordingly, effect on moles should be monitored.Dosage:
Melanotan II is an effective injectable peptide product to enhance ability to tan. Dosing is typically 0.5 to 1.0 mg/day, and the total amount needed for good effect is typically 30-40 mg, though for individuals of medium darkness already, it may be as low as 10 mg for significant effect. MT-II can also be used to enhance tendency to penile erection, but frequency of such use needs to be limited to avoid excessive total effect on skin pigmentation.The products maybe you are interested also:NameCAS CodeCJC-1295 (2mg/vial,10vials/kit)863288-34-0CJC-1295 DAC (Drug Affinity Complex) (2mg/vial,10vials/kit)
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