Size 00 Vegetarian Transparent Color HPMC Empty Capsule Shell

Hydroxypropyl methyl cellulose (HPMC) empty capsule
Hydroxypropyl methyl cellulose empty capsule as a new plant capsule, with greater dissolution, high humidity tolerance, low steam through quantity etc, and with its unique sources, mature technology and variaus technical advantage, for preparation industry provides a larger development space.
Vegetable empty capsule features:
> Low moisture content , HPMC capsules cantains 60% less moisture than gelatin capsule.
> Resilient and non brittle at low moisture content. it is perfect for hydroscopic materials.
> Excellent stability.
> Easy to go further coating with GRAS or traditional formula.
> Environment friendly and health conscious.SPECIFICATION OF EMPTY CAPSULESize0001234Weightmg1189676614838Tolerance mg+7+6±5±4±3±3CapacityCapsule volume ml0.950.680.500.370.300.21
Powder denisity/
Capsule capacity mg0.6g/ml5464083002221801260.8g/ml7285444002962401681g/ml9106805003703002101.2g/ml1092816600444360252Length of the capsule parts (body and cap)Body inches0.7960.7260.6540.6010.5350.480Tolerance inches±0.018±0.018±0.018±0.018±0.018±0.018Body mm20.2218.4416.6115.2713.5912.19Tolerance mm±0.46±0.46±0.46±0.46±0.46±0.46cap Capinches0.4620.4220.3850.3520.3180.284Tolerance inches±0.018±0.018±0.018±0.018±0.018±0.018Cap mm11.7410.729.788.948.087.21Tolerance mm±0.46±0.46±0.46±0.46±0.46±0.46External diameterBody inches0.3220.2890.2610.2390.2190.199Body mm8.187.346.636.075.575.05Cap inches0.3360.3000.2720.2500.2290.209Tolerance mm8.537.646.916.355.825.32Overall closed lengthInches0.9170.8540.7650.7090.6260.536Tolerance inches±0.012±0.012±0.012±0.012±0.012±0.012mm23.321.719.418.015.914.3Tolerance mm±0.3±0.3±0.3±0.3±0.3±0.3
PHYSIOCHEMICAL STANDARDS OF GELATIN EMPTY CAPSULEItemRequireldentificationPositively reactionDegree of tightness≤1/10Brittle≤5/50Disintegration≤10minHeavy metals≤40ppmSulfita≤O.01%C2H5CIlOIn line with the provisionsLoss on drying12.5% - 17.5%ASHTransparent≤2.0%Translucent≤3.0%Opaque≤5.0%Viscosity≥60mm2/sChrominm≤2ppmEthylene Oxide≤0.0001%Metyl Parabe≤0.05%MICROBIALBacteria≤lOOO piece/gMildew≤lOO piece/gEscherichia coliNEGSalmonellaNEG
FUNDAMENTAL REQUIREMENT OF FILLING ROOM
To keep thermometer and hygrometer qualified
> The instruments should be kept in good working conditions
> To be examined and maintained regula rly
> To be put in a suitable place for away from the air outlet of air conditioner
> To be calibrated to their qualification at regular intervals by concerning measuring department
The recommended filling room environment
Temperature:20°C to 24°C Relative humidity: 45 %-55 %
Environmental Control
> The filling room should be conformed to the GMP requirement
> To note down the temperature and humidity twice a shift
> Air conditioner . dehumidizer and humidifier are ready for use
> The filling room operation procedure should be observed
Miscellaneous
> To avoid heat generation source radiation
> Filling room to be well insulated from outside
> To use curtains if sunlight shines directly into the room through windows
Storage and using of capsules:
> Capsules should be stored in the room with the temperature between l01: t0 251: and the relative humidity of 35%-65%.
> Capsule cartons should be kept away from walls and a certain distance from the floor to avoid moisture.
> Tighten up tha plastic bags with capsules inside
> Avoid direct sunshine, keep away from heat generation and water sources.
> Capsule cartons should be stored in the place where there is the similar condition with filling room at least half-day before they can be open for filling, in case there are big differences of the temperature and humidity between warehouse and filling room.
> Scoop out and put down capsules gently to prevent defects of mashes, loose pieces and Snap-Fit closed etc. Caused by the improper handling of the capsules.
> No capsules can be used for those touched by bare hands.