USA Warehouse High Purity, Factory Supply Free Samples manufacturer / supplier in China, offering Whitening & Freckle Removing Series Cosmetic Peptide Decapeptide-12 CAS. 137665-91-9, Factory Supply High Quality Wholesale Price Synephrine HCl 99% Purity CAS 5985-28-4, Factory Supply Wholesale Price High Quality Higenamine HCl 99% Purity CAS 11041-94-4 and so on.
Min. Order / Reference FOB Price | |
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100 Grams | US $22.00/ Grams |
Local Area: | Hubei, China |
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R&D Capacity: | OEM, ODM, Other |
Payment Terms: | LC, T/T, PayPal |
Powder: | Yes |
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Customized: | Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Product name
Agomelatine
CAS No.
138112-76-2
Molecular Formula
C15H17NO2
Molecular weight
243.30098
Purity
99%
Grade Standard
Medicine Grade
Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively.
Agomelatine is one kind of off-white or white crystalline powder or white solid. The IUPAC Name of this chemical is N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide. This chemical belongs to Aromatics Compounds;Aromatics;Neurochemicals;APIS. It should be store at -20°C Freezer. Agomelatine Solubility: Soluble in Chloroform and Methanol. DMSO ≥49mg/mL Water <1mg/mL Ethanol ≥49mg/mL.
As a Pharmaceutical Intermediates, Agomelatine is used in the treatment of major depressive disorder, emotional disorder. Agomelatine is used in the treatment of major depressive disorder, emotional disorder. The drug substance for Nervous system. Antidepressant, anxiolytic, adjusting the rhythm of sleep and regulating biological clock. Agomelatine is a melatoninergic agonist and selective antagonist of 5-ht2c receptors. Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Agomelatine is also a potent agonist at melatonin receptors which makes it the first melatonergic antidepressant.
Agomelatine can help regulate your'body clock' (circadian rhythm) with positive benefits on mood and sleepin depression Agomelatine is used in the treatment of depression or to help prevent depression returning, and isonly available with a doctor's prescription. The symptoms of depression vary from one person toanother, but commonly include persistent sadness, loss of interest in favourite activities, feelings of worthlessness, sleep problems, feeling of being slowed down, feelings of anxiety or changes in appetite and weight. Changes in your daily sleep and appetite patterns are examples of disturbances of your body clock that occur commonly indepression.