China Cosmetic Lyophilized Powder P21 Peptide 6c Intermediate Powder

Cosmetic Lyophilized powder P21 peptide 6c intermediate powder
10mg/vial, 10 vials per box
raw powder is available too
Physical Characters and specifications

Product nameP21 peptideSequence Ac-DGGL(A)G-NH2CAS No.N/AMolecular FormulaC30H54N6O5Molecular weight579.3Source Synthetic Purity98% min

Description:

Researchers found that the main neurogenic and memory enhancing effects from Cerebrolysin were due to its ability to react to human CNTF. So the researchers narrowed their search, and found that an 11-mer peptide, labeled peptide 6 (Ac-VGDGGLFEKKL-NH2), enhanced hippocampus-dependent learning and memory, increased neurogenesis, and neuronal plasticity. They then determined the most active sub-sequence in the peptide called peptide 6C (Ac-DGGL-NH2). However, this peptide sequence showed to have poor blood brain barrier permeability, and was easily broken down by plasma enzymes. To combat this, they added an adamantane moiety to the N-terminus of the peptide sequence. This highly lipophilic tricyclic alkane greatly increased the BBB permeability, and protected the peptide from enzymatic degredation.