China Skincare Kgf Ampoule 148348-15-6 Keratinocyte Growth Cosmetic Factor Powder

SkinCare KGF 148348-15-6 Keratinocyte Grow th Factor cosmetic powder
EGF, FGF, KGF, SOD, FOXO4-dri and all cosmetic powder
raw powder, freeze-dired fine powder all available
Physical Characters and specifications

NameKGFCAS148348-15-6Grade StandardInjection gradeCOAPls contact with Senwayer freelyMOQ10000IU/vial, MOQ is 1000 vialsAppearanceWhite powderPurity, % (by RP-HPLC)95%Storage2 - 8 degreeEXP time3 years

Keratinocyte Grow th Factor-2 (KGF-2) was originally identified from rat embryos by
homology-based polymerase chain reaction. Human and mouse KGF-2 were subsequently cloned. The human KGF-2 cDNA encodes a 208 amino acid residue protein with a hydrophobic amino-terminal signal peptide. Human KGF-2 shares approximately 92% and 95% amino acid sequence identity with mouse and rat KGF-2, respectively. Among the FGF family members, KGF-2 is most closely related to FGF-7. KGF-2 transcripts has been shown to be most abundant in the embryo and adult lungs. Recombinant KGF-2 preparations have been shown to be mitogenic for epithelial and epidermal cells but not fibroblasts. based on its in vitro biological activities and in vivo expression pattern, KGF-2 has been proposed to play unique roles in the brain, in lung development, wound healing and limb bud formation.


Molecular Weight: Approximately 19.3 kDa, 170 amino acid residues consisting of Methionine and the mature human KGF-2 (amino acid residues 40 - 208).


Biological Activity: Fully biologically active. The ED50 is ≤0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg, as determined by proliferation of BaF3 cells expressing FGF receptors.

Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

Endotoxin < 1EU/ug of grow th factor as determined by LAL method.

Reconstitution: Reconstitute in sterile distilled water containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL.
Notes:

This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.

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