China USP Grade Estriol Micro Powder CAS 50-27-1 Female Hormone

USP grade Estriol Micro powder CAS 50-27-1 Female Hormone

Physical Characters and specifications

ItemSpecifications Product nameEstriol micro powderCAS No.50-27-1Molecular FormulaC18H24O3Molecular weight288.38EINECS NO.200-022-2Grade StandardUSP GradeCOAPls contact Senwayer freelyMOQ100gAppearanceWhite PowderPurity99%minStorage condition-20 degree FreezerShelf life2 years

Description:

Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estrone. Levels of estriol in women who are not pregnant are almost undetectable. During PREGNANCY, a large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.

Function

In pregnant women with multiple sclerosis, estriol reduces the disease's symptoms noticeably, according to researchers at UCLA's Geffen Medical School.
Estriol can be a weak or strong estrogen depending on if it is given acutely or chronically when given to immature animals, but is an antagonist when given in combination with estradiol. Estriol may play a role in the development of breast cancer, but based on in vitro research, does appear to act as an antagonist to the G-protein coupled estrogen receptor. Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDAor Health Canada. Though initial research in the 1970s suggested it could be used therapeutically as an estrogen, subsequent research failed to confirm this hypothesis.

Therapeutic use:
In pregnant women with multiple sclerosis (MS), estriol reduces the disease's symptoms noticeably, according to researchers at UCLA's Geffen Medical School.

Lab test report