High Quality Oxytetracycline Injection 5% 10% 20% 30%

PHARMACOLOGY:
Oxytetracycline is primarily bacteriostatic and is thought to exert its antimicrobial effect by the inhibition of protein synthesis. Oxytetracycline is active against a wide range of gram-negative and gram-positive organisms. The drugs in the tetracycline class have closely similar antimicrobial spectra and cross resistance among them is common. Micro-organisms may be considered susceptible of the M. I. C. (Minimum inhibitory concentration) is not more than 4.0 mcg/ml and intermediate if the M. I. C. Is 4.0 to 12.5mcg/ml.PHARMACOKINETICS:
Oxytetracyclines are readily absorbed and are bound to plasma proteins in varying degree. They are concentrated by the liver in the bile and excreted in the urine and faeces at high concentrations and in a biologically active form. Oxytetracycline is the least lipid soluble derivative among tetracycline class.INDICATIONS:
Oxytetracycline is indicated in infections caused by the following micro-organisms. Rickettsiae (rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsial pox and tick fevers). Mycoplasma pneumoniae agents of psittacosis and ornithosis agents of lymphogranuloma venereum and granuloma inguinale; The spirochaetal agent of relapsing fever (Borrelia recurrentis).CONTRAINDICATIONS:
The drug is contraindicated in animals who have shown hypersensitivity to any of the tetracyclines.WARNINGS:
Animal studies indicate that oxytetracycline crosses the placenta and found in fetal tissues and can have toxic effects on the developing foetus (often related to retardation of skeletal development)
Evidence of embryotoxicity has also been noted in animals treated early in pregnancy. The usage of Oxytetracycline during tooth development (last half of pregnancy, infancy) may cause permanent discolouration of teeth (Yellow-Grey-Brown). Therefore should not be used in this age group unless other drugs are not likely to be effective or are contraindicated. Oxytetracycline are present in the milk of lactating animal who are taking this drug.PRECAUTIONS:
Oxytetracycline intramuscular solution should be injected well within the body of a relatively large muscle. As with all intramuscular injections aspiration is necessary to help avoid inadvertent injection into a blood vessel. If any super infection occurs the oxytetracycline should be discontinued and appropriate therapy instituted. Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, It is advisable to avoid giving tetracycline drugs in conjunction with penicillin.
ADVERSE REACTIONS:DOSAGE AND ADMINISTRATION:
Deep Intramuscular Injections:
Cattle, Horse, Camel, Sheep, Goat, Pig:
10mg-20mg per kg body weightWITHDRAWAL PERIOD:
Meat: 7 days
Milk: 28 days